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Docetaxel

Discovery priority: MEDIUM · POSSIBLE / INVESTIGATE

Discovery priority ≠ investment recommendation. These are observation labels, not verified canonical products. Buyer qualification: UNKNOWN.

Why investigate?

Why stranded (event context): efficacy failure; inadequate public evidence; recruitment/execution failure; safety failure; trial-design failure

Why now: Historical lead requires current reconfirmation; no fresh transaction catalyst established

Company/trial failed before biology? UNKNOWN

Biology implicated: UNCLEAR · Failure context: MIXED

MODEL INFERENCE · LOW confidence. Explicit asset-linked program event or documented experimental trial arm, stop scope, dated recency and biological cautions; no publication count or buyer-gate input.

Current control: UNKNOWN · Restart: UNKNOWN · Development reuse: UNKNOWN

Next diligence: Confirm present program status and exact product identity, then trace scoped rights/data/CMC and review arm-level human outcomes.

Existing buyer gates

Human Signal: UNKNOWN

Cheap Truth: UNKNOWN

Clean Rights: UNKNOWN

Market Pull: UNKNOWN

No event or publication count supplies missing gate evidence. Existing reviewed opportunities remain in their original records.

Evidence timeline

2026-04-21 · trial:NCT02257619

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

Sponsor decision to not initiate part 2 due to slow enrollment and competing trials.

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: recruitment/execution failure · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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2026-05-15 · trial:NCT00183937

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

Sponsor stopped study early.

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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2026-06-18 · trial:NCT00253318

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

Toxicity and Lack of Efficacy

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: efficacy failure; safety failure · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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  "url": "https://clinicaltrials.gov/study/NCT00253318"
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2026-06-24 · trial:NCT01012297

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

The study was targeted to accrue 130 patients, but closed early for futility.

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: efficacy failure · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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  "url": "https://clinicaltrials.gov/study/NCT01012297"
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2026-07-17 · trial:NCT00707473

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

\<75% participation

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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  "url": "https://clinicaltrials.gov/study/NCT00707473"
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2026-09-01 · trial:NCT01810913

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

Other - Assessing accrual feasibility

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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  "url": "https://clinicaltrials.gov/study/NCT01810913"
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2026-09-01 · trial:NCT05378763

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

The study has not enrolled any patients. The study design is under discussion and will likely be redesigned in consultation with the FDA.

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: trial-design failure · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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2026-09-02 · trial:NCT03367676

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

Due to slower than anticipated enrollment, the study was terminated early after 78 patients were recruited.

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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Freshness is claim-specific

Fetching an old filing today does not establish current ownership or program status.

pipeline · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

sec · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

rights · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

contact · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

patent_assignment · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.118260+00:00

clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.118260+00:00

clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.118260+00:00

clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.118260+00:00

clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.118260+00:00

clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.930865+00:00

clinicaltrials · STALE · AREA[OverallStatus]SUSPENDED AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:04.075140+00:00

clinicaltrials · STALE · AREA[OverallStatus]SUSPENDED AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:05.182528+00:00

Registry observations (12)

NCT00707473 · TERMINATED · PHASE2 · Locally Advanced Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma; Nasal Cavity and Paranasal Sinus Poorly Differentiated Carcinoma; Sinonasal Undifferentiated Carcinoma; Stage II Nasal Cavity and Paranasal Sinus Cancer AJCC v8; Stage III Nasal Cavity and Paranasal Sinus Cancer AJCC v8; Stage IVA Nasal Cavity and Paranasal Sinus Cancer AJCC v8; Stage IVB Nasal Cavity and Paranasal Sinus Cancer AJCC v8 · Trial sponsor M.D. Anderson Cancer Center

Reported aliases: Docecad; RP56976; Taxotere; Taxotere Injection Concentrate. Identity, treatment role and exposure require review.

NCT01012297 · TERMINATED · PHASE3 · Recurrent Uterine Corpus Sarcoma; Stage IIIA Uterine Sarcoma; Stage IIIB Uterine Sarcoma; Stage IIIC Uterine Sarcoma; Stage IVA Uterine Sarcoma; Stage IVB Uterine Sarcoma; Uterine Corpus Leiomyosarcoma · Trial sponsor National Cancer Institute (NCI)

Reported aliases: RP56976; Taxotere; Taxotere Injection Concentrate. Identity, treatment role and exposure require review.

NCT00253318 · TERMINATED · PHASE1 · Breast Cancer · Trial sponsor M.D. Anderson Cancer Center

Reported aliases: Taxotere. Identity, treatment role and exposure require review.

NCT00183937 · TERMINATED · PHASE2 · Prostate Cancer · Trial sponsor University of Southern California

Reported aliases: None. Identity, treatment role and exposure require review.

NCT02257619 · TERMINATED · PHASE2 · NSCLC (Non-small Cell Lung Carcinoma) · Trial sponsor Incyte Corporation

Reported aliases: None. Identity, treatment role and exposure require review.

NCT03367676 · TERMINATED · PHASE2 · Breast Cancer · Trial sponsor Ruijin Hospital

Reported aliases: None. Identity, treatment role and exposure require review.

NCT01810913 · SUSPENDED · PHASE2, PHASE3 · Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma; Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7; Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7; Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7; Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7; Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7; Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7; Stage IV Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7; Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7 · Trial sponsor National Cancer Institute (NCI)

Reported aliases: Docecad; RP 56976; RP-56976; RP56976; Taxotere; Taxotere Injection Concentrate. Identity, treatment role and exposure require review.

NCT05378763 · SUSPENDED · PHASE3 · NSCLC · Trial sponsor Spectrum Pharmaceuticals, Inc

Reported aliases: None. Identity, treatment role and exposure require review.

NCT01350817 · COMPLETED · PHASE2 · Non Small Cell Lung Cancer · Trial sponsor University Hospital, Limoges

Reported aliases: None. Identity, treatment role and exposure require review.

NCT01658462 · COMPLETED · PHASE2 · Breast Cancer · Trial sponsor Centre Oscar Lambret

Reported aliases: Taxotere. Identity, treatment role and exposure require review.

NCT01652469 · COMPLETED · PHASE3 · Carcinoma, Non-Small-Cell Lung · Trial sponsor ETOP IBCSG Partners Foundation

Reported aliases: Taxotere (Sanofi-Aventis). Identity, treatment role and exposure require review.

NCT07829900 · COMPLETED · · HER2-Positive Breast Cancer; Advanced Breast Cancer · Trial sponsor Xin Li

Reported aliases: None. Identity, treatment role and exposure require review.

Back to discovery