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rituximab

Discovery priority: MEDIUM · POSSIBLE / INVESTIGATE

Discovery priority ≠ investment recommendation. These are observation labels, not verified canonical products. Buyer qualification: UNKNOWN.

Why investigate?

Why stranded (event context): inadequate public evidence; supply failure

Why now: Historical lead requires current reconfirmation; no fresh transaction catalyst established

Company/trial failed before biology? UNKNOWN

Biology implicated: UNCLEAR · Failure context: CMC/OPERATIONS

MODEL INFERENCE · LOW confidence. Explicit asset-linked program event or documented experimental trial arm, stop scope, dated recency and biological cautions; no publication count or buyer-gate input.

Current control: UNKNOWN · Restart: UNKNOWN · Development reuse: UNKNOWN

Next diligence: Confirm present program status and exact product identity, then trace scoped rights/data/CMC and review arm-level human outcomes.

Existing buyer gates

Human Signal: UNKNOWN

Cheap Truth: UNKNOWN

Clean Rights: UNKNOWN

Market Pull: UNKNOWN

No event or publication count supplies missing gate evidence. Existing reviewed opportunities remain in their original records.

Evidence timeline

2025-05-06 · trial:NCT00550342

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

Problems with drug supply

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: supply failure · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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    "failed": false,
    "last_checked": 1790026982.205955,
    "last_success": 1790026982.205955,
    "live_verified": true,
    "scope": "AREA[OverallStatus]WITHDRAWN AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL)"
  },
  "path": "protocolSection.armsInterventionsModule.interventions",
  "raw_hash": "12dba2f64d20d48c47f4c2e04478803287ca92675724e452ceace13362b9457a",
  "raw_path": "research/obz7_sources/12dba2f64d20d48c47f4c2e04478803287ca92675724e452ceace13362b9457a.json",
  "request_params": {
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    "query.term": "AREA[OverallStatus]WITHDRAWN AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL)",
    "sort": "LastUpdatePostDate:desc"
  },
  "request_url": "https://clinicaltrials.gov/api/v2/studies",
  "type": "clinicaltrials",
  "url": "https://clinicaltrials.gov/study/NCT00550342"
}

2026-09-01 · trial:NCT05279300

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

The sponsor is temporarily pausing the trial to evaluate existing clinical data for long-term benefit-risk and optimize doses and dosing schedule.

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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    "failed": false,
    "last_checked": 1790026985.182528,
    "last_success": 1790026985.182528,
    "live_verified": true,
    "scope": "AREA[OverallStatus]SUSPENDED AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL)"
  },
  "path": "protocolSection.armsInterventionsModule.interventions",
  "raw_hash": "2ca1679dad0f3f17150af6bd4f23c7bb11e653d2dd78fd7c22183dc1902caeed",
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  "request_params": {
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    "query.term": "AREA[OverallStatus]SUSPENDED AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL)",
    "sort": "LastUpdatePostDate:desc"
  },
  "request_url": "https://clinicaltrials.gov/api/v2/studies",
  "type": "clinicaltrials",
  "url": "https://clinicaltrials.gov/study/NCT05279300"
}

Freshness is claim-specific

Fetching an old filing today does not establish current ownership or program status.

pipeline · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

sec · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

rights · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

contact · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

patent_assignment · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

clinicaltrials · STALE · AREA[OverallStatus]WITHDRAWN AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:02.205955+00:00

clinicaltrials · STALE · AREA[OverallStatus]SUSPENDED AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:05.182528+00:00

Registry observations (4)

NCT00550342 · WITHDRAWN · PHASE2 · Focal Segmental Glomerulosclerosis (FSGS) · Trial sponsor National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Reported aliases: Rituxan. Identity, treatment role and exposure require review.

NCT05279300 · SUSPENDED · PHASE1 · Advanced Solid Tumor; Advanced Lymphoma · Trial sponsor CStone Pharmaceuticals

Reported aliases: None. Identity, treatment role and exposure require review.

NCT01842386 · COMPLETED · PHASE1 · Pulmonary Alveolar Proteinosis (PAP); Severe Mucocutaneous Candidiasis · Trial sponsor National Institute of Allergy and Infectious Diseases (NIAID)

Reported aliases: None. Identity, treatment role and exposure require review.

NCT01135641 · COMPLETED · PHASE2 · Graft Versus Host Disease · Trial sponsor Nantes University Hospital

Reported aliases: None. Identity, treatment role and exposure require review.

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