Find → Understand → Decide
Tacrolimus
Discovery priority: MEDIUM · POSSIBLE / INVESTIGATE
Discovery priority ≠ investment recommendation. These are observation labels, not verified canonical products. Buyer qualification: UNKNOWN.
Why investigate?
Why stranded (event context): financing failure; inadequate public evidence
Why now: Historical lead requires current reconfirmation; no fresh transaction catalyst established
Company/trial failed before biology? UNKNOWN
Biology implicated: UNCLEAR · Failure context: CORPORATE/FINANCIAL
MODEL INFERENCE · LOW confidence. Explicit asset-linked program event or documented experimental trial arm, stop scope, dated recency and biological cautions; no publication count or buyer-gate input.
Current control: UNKNOWN · Restart: UNKNOWN · Development reuse: UNKNOWN
Next diligence: Confirm present program status and exact product identity, then trace scoped rights/data/CMC and review arm-level human outcomes.
Existing buyer gates
Human Signal: UNKNOWN
Cheap Truth: UNKNOWN
Clean Rights: UNKNOWN
Market Pull: UNKNOWN
No event or publication count supplies missing gate evidence. Existing reviewed opportunities remain in their original records.
Evidence timeline
2026-03-30 · trial:NCT02333162
Registry update date, not proven program-stop date
SOURCE TEXT · Exact source
Enrollment on hold pending amendment
Trial reason is not attributed to every intervention; comparator/combination context needs review.
Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM
Provenance and retrieval scope
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"type": "clinicaltrials",
"url": "https://clinicaltrials.gov/study/NCT02333162"
}2026-05-27 · trial:NCT01135329
Registry update date, not proven program-stop date
SOURCE TEXT · Exact source
The stopping rule was met and hence the study was closed
Trial reason is not attributed to every intervention; comparator/combination context needs review.
Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM
Provenance and retrieval scope
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"url": "https://clinicaltrials.gov/study/NCT01135329"
}2026-09-03 · trial:NCT07349771
Registry update date, not proven program-stop date
SOURCE TEXT · Exact source
Sponsor declined to fund study due to inability to agree on IP.
Trial reason is not attributed to every intervention; comparator/combination context needs review.
Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM
Provenance and retrieval scope
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}2026-09-10 · trial:NCT06680661
Registry update date, not proven program-stop date
SOURCE TEXT · Exact source
insufficient funding
Trial reason is not attributed to every intervention; comparator/combination context needs review.
Interpretation: financing failure · AUTO_INFERRED · MEDIUM
Provenance and retrieval scope
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}Freshness is claim-specific
Fetching an old filing today does not establish current ownership or program status.
pipeline · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN
sec · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN
rights · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN
contact · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN
patent_assignment · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN
clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.118260+00:00
clinicaltrials · STALE · AREA[OverallStatus]WITHDRAWN AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:03.011815+00:00
clinicaltrials · STALE · AREA[OverallStatus]SUSPENDED AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:04.075140+00:00
clinicaltrials · STALE · AREA[OverallStatus]SUSPENDED AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:05.182528+00:00
Registry observations (4)
NCT01135329 · TERMINATED · PHASE2 · Lymphoma; Leukemia; Myelodysplastic Syndrome · Trial sponsor Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Reported aliases: FK506; FK-506; Prograf. Identity, treatment role and exposure require review.
NCT07349771 · WITHDRAWN · PHASE2 · Hematopoietic and Lymphatic System Neoplasm · Trial sponsor Mayo Clinic
Reported aliases: FK 506; FK-506; FK506; Fujimycin; Hecoria; Prograf; Protopic; Tacforius. Identity, treatment role and exposure require review.
NCT02333162 · SUSPENDED · PHASE1 · Previously Treated Myelodysplastic Syndrome; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Hematologic Malignancy · Trial sponsor University of Chicago
Reported aliases: Advagraf; FK 506. Identity, treatment role and exposure require review.
NCT06680661 · SUSPENDED · PHASE2 · Acute Myelogenous Leukemia; Acute Lymphatic Leukemia; Chronic Myelogenous Leukemia; Myelodysplastic Syndromes; Myelodysplastic Syndrome Other; Chronic Myelomonocytic Leukemia; Lymphoma; Hodgkin Lymphoma · Trial sponsor Leland Metheny
Reported aliases: None. Identity, treatment role and exposure require review.