Find → Understand → Decide
Metformin
Discovery priority: MEDIUM · POSSIBLE / INVESTIGATE
Discovery priority ≠ investment recommendation. These are observation labels, not verified canonical products. Buyer qualification: UNKNOWN.
Why investigate?
Why stranded (event context): efficacy failure; financing failure; inadequate public evidence; strategic reprioritization
Why now: Historical lead requires current reconfirmation; no fresh transaction catalyst established
Company/trial failed before biology? UNKNOWN
Biology implicated: UNCLEAR · Failure context: MIXED
MODEL INFERENCE · LOW confidence. Explicit asset-linked program event or documented experimental trial arm, stop scope, dated recency and biological cautions; no publication count or buyer-gate input.
Current control: UNKNOWN · Restart: UNKNOWN · Development reuse: UNKNOWN
Next diligence: Confirm present program status and exact product identity, then trace scoped rights/data/CMC and review arm-level human outcomes.
Existing buyer gates
Human Signal: UNKNOWN
Cheap Truth: UNKNOWN
Clean Rights: UNKNOWN
Market Pull: UNKNOWN
No event or publication count supplies missing gate evidence. Existing reviewed opportunities remain in their original records.
Evidence timeline
2026-03-12 · trial:NCT01351753
Registry update date, not proven program-stop date
SOURCE TEXT · Exact source
Lack of funding
Trial reason is not attributed to every intervention; comparator/combination context needs review.
Interpretation: financing failure · AUTO_INFERRED · MEDIUM
Provenance and retrieval scope
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"url": "https://clinicaltrials.gov/study/NCT01351753"
}2026-07-10 · trial:NCT07007221
Registry update date, not proven program-stop date
SOURCE TEXT · Exact source
Study was not initiated because funding was not received.
Trial reason is not attributed to every intervention; comparator/combination context needs review.
Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM
Provenance and retrieval scope
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"url": "https://clinicaltrials.gov/study/NCT07007221"
}2026-07-10 · trial:NCT02571608
Registry update date, not proven program-stop date
SOURCE TEXT · Exact source
Study halted prematurely, prior to enrollment of first participant
Trial reason is not attributed to every intervention; comparator/combination context needs review.
Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM
Provenance and retrieval scope
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}2026-09-08 · trial:NCT05580250
Registry update date, not proven program-stop date
SOURCE TEXT · Exact source
The sponsor made a business decision to withdraw the trial.
Trial reason is not attributed to every intervention; comparator/combination context needs review.
Interpretation: strategic reprioritization · AUTO_INFERRED · MEDIUM
Provenance and retrieval scope
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}2026-09-18 · trial:NCT00814372
Registry update date, not proven program-stop date
SOURCE TEXT · Exact source
MBX-102 did not meet the target efficacy profile of HbA1c change.
Trial reason is not attributed to every intervention; comparator/combination context needs review.
Interpretation: efficacy failure · AUTO_INFERRED · MEDIUM
Provenance and retrieval scope
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}Freshness is claim-specific
Fetching an old filing today does not establish current ownership or program status.
pipeline · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN
sec · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN
rights · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN
contact · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN
patent_assignment · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN
clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.118260+00:00
clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.118260+00:00
clinicaltrials · STALE · AREA[OverallStatus]WITHDRAWN AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:03.011815+00:00
clinicaltrials · STALE · AREA[OverallStatus]WITHDRAWN AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:03.011815+00:00
clinicaltrials · STALE · AREA[OverallStatus]WITHDRAWN AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:03.011815+00:00
Registry observations (9)
NCT00814372 · TERMINATED · PHASE2 · Type 2 Diabetes Mellitus · Trial sponsor Gilead Sciences
Reported aliases: None. Identity, treatment role and exposure require review.
NCT01351753 · TERMINATED · PHASE2 · Obesity; Metabolic Syndrome X · Trial sponsor University of Iowa
Reported aliases: None. Identity, treatment role and exposure require review.
NCT05580250 · WITHDRAWN · PHASE1 · Healthy · Trial sponsor Eli Lilly and Company
Reported aliases: None. Identity, treatment role and exposure require review.
NCT07007221 · WITHDRAWN · PHASE2 · Depression; Hiv · Trial sponsor University of Minnesota
Reported aliases: None. Identity, treatment role and exposure require review.
NCT07007221 · WITHDRAWN · PHASE2 · Depression; Hiv · Trial sponsor University of Minnesota
Reported aliases: None. Identity, treatment role and exposure require review.
NCT07007221 · WITHDRAWN · PHASE2 · Depression; Hiv · Trial sponsor University of Minnesota
Reported aliases: None. Identity, treatment role and exposure require review.
NCT07007221 · WITHDRAWN · PHASE2 · Depression; Hiv · Trial sponsor University of Minnesota
Reported aliases: None. Identity, treatment role and exposure require review.
NCT02571608 · WITHDRAWN · PHASE4 · Diabetes Mellitus Type 2 · Trial sponsor McMaster University
Reported aliases: Group A. Identity, treatment role and exposure require review.
NCT00720161 · COMPLETED · NA · Spina Bifida; Neuromuscular Diseases · Trial sponsor Universitaire Ziekenhuizen KU Leuven
Reported aliases: None. Identity, treatment role and exposure require review.