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Gemcitabine

Discovery priority: MEDIUM · POSSIBLE / INVESTIGATE

Discovery priority ≠ investment recommendation. These are observation labels, not verified canonical products. Buyer qualification: UNKNOWN.

Why investigate?

Why stranded (event context): inadequate public evidence; strategic reprioritization

Why now: Historical lead requires current reconfirmation; no fresh transaction catalyst established

Company/trial failed before biology? UNKNOWN

Biology implicated: UNCLEAR · Failure context: CORPORATE/FINANCIAL

MODEL INFERENCE · LOW confidence. Explicit asset-linked program event or documented experimental trial arm, stop scope, dated recency and biological cautions; no publication count or buyer-gate input.

Current control: UNKNOWN · Restart: UNKNOWN · Development reuse: UNKNOWN

Next diligence: Confirm present program status and exact product identity, then trace scoped rights/data/CMC and review arm-level human outcomes.

Existing buyer gates

Human Signal: UNKNOWN

Cheap Truth: UNKNOWN

Clean Rights: UNKNOWN

Market Pull: UNKNOWN

No event or publication count supplies missing gate evidence. Existing reviewed opportunities remain in their original records.

Evidence timeline

2015-06-23 · trial:NCT00624182

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

SUSPENDED

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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2026-09-01 · trial:NCT05279300

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

The sponsor is temporarily pausing the trial to evaluate existing clinical data for long-term benefit-risk and optimize doses and dosing schedule.

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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  "url": "https://clinicaltrials.gov/study/NCT05279300"
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2026-09-04 · trial:NCT06050252

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

Other - evaluation of patients on first stage

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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  "type": "clinicaltrials",
  "url": "https://clinicaltrials.gov/study/NCT06050252"
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2026-09-14 · trial:NCT04191135

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

Business Reasons

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: strategic reprioritization · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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  "type": "clinicaltrials",
  "url": "https://clinicaltrials.gov/study/NCT04191135"
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2026-09-17 · trial:NCT00421096

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

Problems of recruitment

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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  "type": "clinicaltrials",
  "url": "https://clinicaltrials.gov/study/NCT00421096"
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Freshness is claim-specific

Fetching an old filing today does not establish current ownership or program status.

pipeline · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

sec · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

rights · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

contact · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

patent_assignment · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.118260+00:00

clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.930865+00:00

clinicaltrials · STALE · AREA[OverallStatus]SUSPENDED AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:04.075140+00:00

clinicaltrials · STALE · AREA[OverallStatus]SUSPENDED AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:05.182528+00:00

clinicaltrials · STALE · AREA[OverallStatus]SUSPENDED AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:05.182528+00:00

Registry observations (6)

NCT00421096 · TERMINATED · PHASE2 · Uterine Cervical Cancer · Trial sponsor Centre Oscar Lambret

Reported aliases: None. Identity, treatment role and exposure require review.

NCT04191135 · TERMINATED · PHASE2 · Triple Negative Breast Neoplasms · Trial sponsor Merck Sharp & Dohme LLC

Reported aliases: GEMZAR®. Identity, treatment role and exposure require review.

NCT00624182 · SUSPENDED · PHASE1 · Bile Duct Cancer · Trial sponsor Akita University Hospital

Reported aliases: None. Identity, treatment role and exposure require review.

NCT06050252 · SUSPENDED · PHASE2 · Resectable Intrahepatic Cholangiocarcinoma · Trial sponsor National Cancer Institute (NCI)

Reported aliases: dFdC; dFdCyd; Difluorodeoxycytidine. Identity, treatment role and exposure require review.

NCT05279300 · SUSPENDED · PHASE1 · Advanced Solid Tumor; Advanced Lymphoma · Trial sponsor CStone Pharmaceuticals

Reported aliases: None. Identity, treatment role and exposure require review.

NCT01352962 · COMPLETED · PHASE1 · Urethral Neoplasms; Neoplasms, Urethral; Cancer of the Urethra; Urethral Cancer · Trial sponsor National Cancer Institute (NCI)

Reported aliases: None. Identity, treatment role and exposure require review.

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