Find → Understand → Decide
Soticlestat
Discovery priority: MEDIUM · POSSIBLE / INVESTIGATE
Discovery priority ≠ investment recommendation. These are observation labels, not verified canonical products. Buyer qualification: UNKNOWN.
Why investigate?
Why stranded (event context): inadequate public evidence; strategic reprioritization
Why now: Historical lead requires current reconfirmation; no fresh transaction catalyst established
Company/trial failed before biology? UNKNOWN
Biology implicated: UNCLEAR · Failure context: CORPORATE/FINANCIAL
MODEL INFERENCE · LOW confidence. Explicit asset-linked program event or documented experimental trial arm, stop scope, dated recency and biological cautions; no publication count or buyer-gate input.
Current control: UNKNOWN · Restart: UNKNOWN · Development reuse: UNKNOWN
Next diligence: Confirm present program status and exact product identity, then trace scoped rights/data/CMC and review arm-level human outcomes.
Existing buyer gates
Human Signal: UNKNOWN
Cheap Truth: UNKNOWN
Clean Rights: UNKNOWN
Market Pull: UNKNOWN
No event or publication count supplies missing gate evidence. Existing reviewed opportunities remain in their original records.
Evidence timeline
2026-08-19 · trial:NCT05309902
Registry update date, not proven program-stop date
SOURCE TEXT · Exact source
Study not needed
Trial reason is not attributed to every intervention; comparator/combination context needs review.
Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM
Provenance and retrieval scope
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"type": "clinicaltrials",
"url": "https://clinicaltrials.gov/study/NCT05309902"
}2026-09-04 · trial:NCT05163314
Registry update date, not proven program-stop date
SOURCE TEXT · Exact source
Due to negative results from phase 3 SKYLINE and SKYWAY studies and unrelated to patient safety it has been determined that supplementary data from TAK-935-3003 study is no longer necessary. Therefore, Takeda has made a decision to close this study
Trial reason is not attributed to every intervention; comparator/combination context needs review.
Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM
Provenance and retrieval scope
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"request_url": "https://clinicaltrials.gov/api/v2/studies",
"type": "clinicaltrials",
"url": "https://clinicaltrials.gov/study/NCT05163314"
}2026-09-04 · trial:NCT06422377
Registry update date, not proven program-stop date
SOURCE TEXT · Exact source
Business decision unrelated to patient safety.
Trial reason is not attributed to every intervention; comparator/combination context needs review.
Interpretation: strategic reprioritization · AUTO_INFERRED · MEDIUM
Provenance and retrieval scope
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"type": "clinicaltrials",
"url": "https://clinicaltrials.gov/study/NCT06422377"
}2026-09-04 · trial:NCT03635073
Registry update date, not proven program-stop date
SOURCE TEXT · Exact source
Due to negative results from phase 3 SKYLINE and SKYWAY studies and unrelated to patient safety it has been determined that supplementary data from TAK-935-18-001 study is no longer necessary. Therefore, Takeda has made a decision to close this study
Trial reason is not attributed to every intervention; comparator/combination context needs review.
Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM
Provenance and retrieval scope
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Freshness is claim-specific
Fetching an old filing today does not establish current ownership or program status.
pipeline · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN
sec · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN
rights · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN
contact · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN
patent_assignment · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN
clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.930865+00:00
clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.930865+00:00
clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.930865+00:00
clinicaltrials · STALE · AREA[OverallStatus]WITHDRAWN AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:03.011815+00:00
Registry observations (4)
NCT05163314 · TERMINATED · PHASE3 · Dravet Syndrome (DS); Lennox Gastaut Syndrome (LGS) · Trial sponsor Takeda
Reported aliases: TAK-935. Identity, treatment role and exposure require review.
NCT06422377 · TERMINATED · PHASE3 · Dravet Syndrome (DS); Lennox-Gastaut Syndrome (LGS) · Trial sponsor Takeda
Reported aliases: TAK-935. Identity, treatment role and exposure require review.
NCT03635073 · TERMINATED · PHASE2 · Epilepsy; Dravet Syndrome (DS); Lennox-Gastaut Syndrome (LGS) · Trial sponsor Takeda
Reported aliases: TAK-935. Identity, treatment role and exposure require review.
NCT05309902 · WITHDRAWN · PHASE1 · Healthy Volunteers · Trial sponsor Takeda
Reported aliases: TAK-935. Identity, treatment role and exposure require review.
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