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Carboplatin

Discovery priority: MEDIUM · POSSIBLE / INVESTIGATE

Discovery priority ≠ investment recommendation. These are observation labels, not verified canonical products. Buyer qualification: UNKNOWN.

Why investigate?

Why stranded (event context): efficacy failure; inadequate public evidence; recruitment/execution failure; strategic reprioritization

Why now: Historical lead requires current reconfirmation; no fresh transaction catalyst established

Company/trial failed before biology? UNKNOWN

Biology implicated: UNCLEAR · Failure context: MIXED

MODEL INFERENCE · LOW confidence. Explicit asset-linked program event or documented experimental trial arm, stop scope, dated recency and biological cautions; no publication count or buyer-gate input.

Current control: UNKNOWN · Restart: UNKNOWN · Development reuse: UNKNOWN

Next diligence: Confirm present program status and exact product identity, then trace scoped rights/data/CMC and review arm-level human outcomes.

Existing buyer gates

Human Signal: UNKNOWN

Cheap Truth: UNKNOWN

Clean Rights: UNKNOWN

Market Pull: UNKNOWN

No event or publication count supplies missing gate evidence. Existing reviewed opportunities remain in their original records.

Evidence timeline

2026-06-23 · trial:NCT00520975

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

Closed early due to slow accrual

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: recruitment/execution failure · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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2026-07-17 · trial:NCT00707473

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

\<75% participation

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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2026-07-31 · trial:NCT05058651

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

End of Initial Phase of Multi-phase protocol

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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2026-09-01 · trial:NCT03604991

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

End of Initial Phase of Multi-phase protocol

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: inadequate public evidence · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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2026-09-11 · trial:NCT05226598

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

MK-7684A-007 was terminated early due to futility. A non-submission CSR, not intended to support any registration, was issued; therefore, an abbreviated CSR was generated.

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: efficacy failure · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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2026-09-14 · trial:NCT04191135

Registry update date, not proven program-stop date

SOURCE TEXT · Exact source

Business Reasons

Trial reason is not attributed to every intervention; comparator/combination context needs review.

Interpretation: strategic reprioritization · AUTO_INFERRED · MEDIUM

Provenance and retrieval scope
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Freshness is claim-specific

Fetching an old filing today does not establish current ownership or program status.

pipeline · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

sec · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

rights · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

contact · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

patent_assignment · PARTIAL · Not independently refreshed for current scoped claim · checked UNKNOWN

clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.118260+00:00

clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2000-01-01,2014-12-31] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.118260+00:00

clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.930865+00:00

clinicaltrials · STALE · AREA[OverallStatus]TERMINATED AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:00.930865+00:00

clinicaltrials · STALE · AREA[OverallStatus]SUSPENDED AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:05.182528+00:00

clinicaltrials · STALE · AREA[OverallStatus]SUSPENDED AND AREA[StartDate]RANGE[2015-01-01,2026-09-21] AND (AREA[InterventionType]DRUG OR AREA[InterventionType]BIOLOGICAL) · checked 2026-09-21T21:43:05.182528+00:00

Registry observations (9)

NCT00707473 · TERMINATED · PHASE2 · Locally Advanced Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma; Nasal Cavity and Paranasal Sinus Poorly Differentiated Carcinoma; Sinonasal Undifferentiated Carcinoma; Stage II Nasal Cavity and Paranasal Sinus Cancer AJCC v8; Stage III Nasal Cavity and Paranasal Sinus Cancer AJCC v8; Stage IVA Nasal Cavity and Paranasal Sinus Cancer AJCC v8; Stage IVB Nasal Cavity and Paranasal Sinus Cancer AJCC v8 · Trial sponsor M.D. Anderson Cancer Center

Reported aliases: Blastocarb; Carboplat; Carboplatin Hexal; Carboplatino; Carbosin; Carbosol; Carbotec; CBDCA; Displata; Ercar; JM-8; Nealorin; Novoplatinum; Paraplatin; Paraplatin AQ; Paraplatine; Platinwas; Ribocarbo. Identity, treatment role and exposure require review.

NCT00520975 · TERMINATED · PHASE3 · Breast Carcinoma; Recurrent Breast Carcinoma; Stage IV Breast Cancer · Trial sponsor National Cancer Institute (NCI)

Reported aliases: CBDCA; JM-8; Paraplatin; NSC-241240. Identity, treatment role and exposure require review.

NCT04191135 · TERMINATED · PHASE2 · Triple Negative Breast Neoplasms · Trial sponsor Merck Sharp & Dohme LLC

Reported aliases: PARAPLATIN®. Identity, treatment role and exposure require review.

NCT05226598 · TERMINATED · PHASE3 · Metastatic Non-Small Cell Lung Cancer · Trial sponsor Merck Sharp & Dohme LLC

Reported aliases: PARAPLATIN®, Paraplatin NovaPlus ®. Identity, treatment role and exposure require review.

NCT03604991 · SUSPENDED · PHASE2, PHASE3 · Clinical Stage II Esophageal Adenocarcinoma AJCC v8; Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage III Esophageal Adenocarcinoma AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8; Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8; Esophageal Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma · Trial sponsor National Cancer Institute (NCI)

Reported aliases: Blastocarb; Carboplat; Carboplatin Hexal; Carboplatino; Carboplatinum; Carbosin; Carbosol; Carbotec; CBDCA; Displata; Ercar; JM-8; JM8; Nealorin; Novoplatinum; Paraplatin; Paraplatin AQ; Paraplatine; Platinwas; Ribocarbo. Identity, treatment role and exposure require review.

NCT05058651 · SUSPENDED · PHASE2, PHASE3 · Advanced Extrapulmonary Neuroendocrine Carcinoma; Metastatic Extrapulmonary Neuroendocrine Carcinoma; Recurrent Extrapulmonary Neuroendocrine Carcinoma; Unresectable Extrapulmonary Neuroendocrine Carcinoma · Trial sponsor National Cancer Institute (NCI)

Reported aliases: Blastocarb; Carboplat; Carboplatin Hexal; Carboplatino; Carboplatinum; Carbosin; Carbosol; Carbotec; CBDCA; Displata; Ercar; JM-8; JM8; Nealorin; Novoplatinum; Paraplatin; Paraplatin AQ; Paraplatine; Platinwas; Ribocarbo. Identity, treatment role and exposure require review.

NCT01352962 · COMPLETED · PHASE1 · Urethral Neoplasms; Neoplasms, Urethral; Cancer of the Urethra; Urethral Cancer · Trial sponsor National Cancer Institute (NCI)

Reported aliases: None. Identity, treatment role and exposure require review.

NCT00632853 · COMPLETED · PHASE3 · Lung Cancer · Trial sponsor Alliance for Clinical Trials in Oncology

Reported aliases: None. Identity, treatment role and exposure require review.

NCT04665856 · COMPLETED · PHASE3 · Small Cell Lung Carcinoma · Trial sponsor Hoffmann-La Roche

Reported aliases: None. Identity, treatment role and exposure require review.

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